![]() 3, 59 The NHFS has shown the most promising results in predicting 30-day mortality in hip-fracture patients. Scores 3 to 5 = well-differentiated (Grade I) Score 6 or 7 = moderately differentiated (Grade II) and score 8 or 9 = poorly-differentiated (Grade III). Among these are the Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity, the Charlson Comorbidity Index, and the Nottingham Hip Fracture Score (NHFS). The minimum score possible is 3 (1+1+1) and the maximum possible is 9 (3+3+3). The final histologic grade is assessed from the sum of all three scores. These 3 scores are added together, making the Nottingham Score. ![]() A numerical scoring system is used where each feature is assigned a score from 1 to 3. The histologic grade is based on the degree of tubule/duct formation, nuclear size and pleomorphism, and mitotic rate. There is a significant correlation between histologic grade and frequency of recurrence, disease free survival, and overall length of survival regardless of clinical stage in invasive breast carcinoma. Grading / Staging / Report 3-5 points, Grade I (well differentiated) 6-7 points, Grade II (moderately differentiated) 8-9 points, Grade III (poorly. Histologic grade is a powerful prognostic indicator. The currently used histologic grading system is known as the Elston-Ellis modification of Scarff-Bloom-Richardson grading system OR Nottingham Combined Histologic Grade. Among the seven possible NSBR scores, Scores 3, 4, and 5 tumors are grouped as low-grade tumors Scores 6 and 7 are intermediate grade and Scores 8 and 9 tumors are consolidated as. The total score is assigned to a grade: Grade I is assigned for a total score of 3 to 5. Do not calculate the score unless all three components are available Note 7: Grade from nodal tissue may be used ONLY when there was never any evidence of primary tumor (T0). These 3 scores are added together, making the Nottingham Score. It is an estimation of the degree of differentiation of the tumor. A combined score of 35 points is designated as grade 1 a combined score of 67 points is grade 2 a combined score of 89 points is grade 3. ![]() The score from each category is added to determine the overall grade as follows: Grade 1 Score of 3, 4, or 5. Grading of ductal carcinoma of breast is performed on the invasive component. Tumours with very few mitotic figures are given a score of 1 while those with many mitotic figures are given a score of 3.
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